bstract The problem of foot and mouth disease (FMD) is of serious concern to the livestock sector in most nations, especially in developing countries. This paper presents the formulation and analysis of a deterministic model for the transmission dynamics of FMD through a contaminated environment. It is shown that the key parameters that drive the transmission of FMD in a contaminated environment are the shedding, transmission, and decay rates of the virus. Using numerical results, it is depicted that the host-to-host route is more severe than the environmental-to-host route. The model is then transformed into an optimal control problem. Using the Pontryagin’s Maximum Principle, the optimality system is determined. Utilizing a gradient type algorithm with projection, the optimality system is solved for three control strategies: optimal use of vaccination, environmental decontamination, and a combination of vaccination and environmental decontamination. Results show that a combination of vaccination and environmental decontamination is the most optimal strategy. These results indicate that if vaccination and environmental decontamination are used optimally during an outbreak, then FMD transmission can be controlled. Future studies focusing on the control measures for the transmission of FMD in a contaminated environment should aim at reducing the transmission and the shedding rates, while increasing the decay rate.
Mugabi, F., Mugisha, J., Nannyonga, B., Kasumba, H., & Tusiime, M. (2019). Parameter-dependent transmission dynamics and optimal control of foot and mouth disease in a contaminated environment. Journal of the Egyptian Mathematical Society, 27(1), 1-21. doi: 10.1186/s42787-019-0058-1
MLA
Francis Mugabi; Joseph Mugisha; Betty Nannyonga; Henry Kasumba; Margaret Tusiime. "Parameter-dependent transmission dynamics and optimal control of foot and mouth disease in a contaminated environment", Journal of the Egyptian Mathematical Society, 27, 1, 2019, 1-21. doi: 10.1186/s42787-019-0058-1
HARVARD
Mugabi, F., Mugisha, J., Nannyonga, B., Kasumba, H., Tusiime, M. (2019). 'Parameter-dependent transmission dynamics and optimal control of foot and mouth disease in a contaminated environment', Journal of the Egyptian Mathematical Society, 27(1), pp. 1-21. doi: 10.1186/s42787-019-0058-1
VANCOUVER
Mugabi, F., Mugisha, J., Nannyonga, B., Kasumba, H., Tusiime, M. Parameter-dependent transmission dynamics and optimal control of foot and mouth disease in a contaminated environment. Journal of the Egyptian Mathematical Society, 2019; 27(1): 1-21. doi: 10.1186/s42787-019-0058-1
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